Author + information
- Stefano Figliozzi, MDa,
- Stefania Rizzo, MDb,
- Chun-Yan Cheng, MD, PhDa,
- Sabino Iliceto, MDa,
- Cristina Basso, MD, PhDb,
- Alida L.P. Caforio, MD, PhDa,∗ ( and )
- Renzo Marcolongo, MDc
- aDivision of Cardiology, Department of Cardiological, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova, Italy
- bCardiovascular Pathology, Department of Cardiological, Thoracic, Vascular Sciences and Public Health, University of Padova, Italy
- cHematology and Clinical Immunology, Department of Medicine, University of Padova, Padova, Italy
- ↵∗Address for correspondence:
Prof. Alida L. P. Caforio, Division of Cardiology, Department of Cardiological, Thoracic, and Vascular Sciences and Public Health, Via N Giustiniani, 2, 35100 Padova, Italy.
A 56-year-old woman with mixed connective tissue disease, who was on maintenance immunosuppression, developed asymptomatic left ventricular dysfunction, ventricular arrhythmia, and high troponin I. Heart catheterization showed normal coronaries and biopsy-proven, virus-negative lymphocytic myocarditis. A biopsy-guided immunosuppression upgrade effectively treated autoimmune myocarditis, which resulted in ventricular function recovery, resolution of arrhythmia, and of troponin release. (Level of Difficulty: Advanced.)
The authors have reported that they have no relationships relevant to the contents of this paper to disclose.
- Received April 9, 2019.
- Revision received May 16, 2019.
- Accepted May 23, 2019.