Author + information
- Vanthana Bharathi, MBBSa,
- Mishita Goel, MDa,b,
- Xavier F. Pombar, DOc,
- Sunita Nathan, MDd and
- Tochukwu M. Okwuosa, DOa,∗ ()
- aDepartment of Internal Medicine, Division of Cardiovascular Diseases, Rush University Medical Center, Chicago, Illinois
- bDepartment of Internal Medicine, Wayne State University, Detroit, Michigan
- cDepartment of Obstetrics & Gynecology, Rush University Medical Center, Chicago, Illinois
- dDepartment of Internal Medicine, Division of Hematology/Oncology, Section of Bone Marrow Transplant and Cell therapy, Rush University Medical Center, Chicago, Illinois
- ↵∗Address for correspondence:
Prof. Tochukwu M. Okwuosa, Department of Internal Medicine, Division of Cardiovascular Diseases, Rush University Medical Center, 1717 West Congress Parkway, Kellogg Building, Suite 328, Chicago, Illinois 60612.
We report the unique case of a patient who recovered cardiac function despite a history of doxorubicin-induced cardiomyopathy, chest radiation therapy, high dose chemotherapy post-allogeneic stem cell transplant, and triplet pregnancy. Data are sparse on doxorubicin-induced cardiomyopathy in pregnant patients, calling for further studies to help formulate management or surveillance recommendations. (Level of Difficulty: Advanced.)
The authors have reported that they have no relationships relevant to the contents of this paper to disclose.
The authors attest they are in compliance with human studies committees and animal welfare regulations of the authors’ institutions and Food and Drug Administration guidelines, including patient consent where appropriate. For more information, visit the JACC: Case Reports author instructions page.
- Received January 29, 2020.
- Revision received April 3, 2020.
- Accepted April 9, 2020.
- 2020 The Authors
- Question 1: What is the differential diagnosis in our patient?
- Question 2: How did we manage this patient?
- Question 3: What are the challenges to pregnancy in a cancer patient post-ASCT and with a history of heart failure?
- Question 4: How was the patient managed during her pregnancy?
- Question 5: What are the learning points from this case?